Furthermore, there is evidence that patients treated for alcohol withdrawal with lorazepam or oxazepam, which also has a relatively short elimination half-life, experience a higher incidence of seizures than patients treated with the long elimination half-life benzodiazepines diazepam or chlordiazepoxide 16, 53, 54. Some drinkers that consume alcohol in quantities outside healthy limits will develop an acute alcohol withdrawal syndrome when they abruptly stop or substantially reduce their alcohol consumption. Most patients manifest a minor symptom complex or syndrome, which may start as early as six to eight hours after an abrupt reduction in alcohol intake.
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